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6-Amino-4-hydroxy-2-naphthalenesulfonic acid

2-Amino-8-naphthol-6-sulfonic acid

CAS: 90-51-7

Molecular Formula: C10H9NO4S

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6-Amino-4-hydroxy-2-naphthalenesulfonic acid - Names and Identifiers

Name 2-Amino-8-naphthol-6-sulfonic acid
Synonyms Gamma Acid
C.I. Developer 3
Galmarine(silymarine soluble)
2-AMINO-8-NAPTHOL-6-SULFONIC ACID
6-AMINO-4-NAPHTHOL-2-SULFONIC ACID
7-AMINO-1-NAPHTHOL-3-SULFONIC ACID
2-Amino-8-naphthol-6-sulfonic acid
7-AMINO-1-HYDROXY-3-SULFONAPHTHALENE
6-Amino-4-hydroxy-2-naphthalinsulfonsure
6-amino-4-hydroxy-2-naphthalenesulfonicaci
6-AMINO-4-HYDROXY-2-NAPHTHALENESULFONIC ACID
4-Hydroxy-6-amino-2-naphthalenesulfonic acid
2-Naphthalenesulfonicacid,6-amino-4-hydroxy-
1-Hydroxy-7-amino-3-naphthalenesulfonic acid
2-Amino-8-hydroxynaphthalene-6-sulfonic acid
6-AMINO-4-HYDROXY-2-NAPHTHALENE-SULPHONICACID
2-Naphthalenesulfonic acid, 6-amino-4-hydroxy-
6-AMINO-4-HYDROXY-2-NAPHTHALENESULFONIC ACID (GAMMA ACID)
CAS 90-51-7
EINECS 202-000-8
InChI InChI=1/C10H9NO4S/c11-7-2-1-6-3-8(16(13,14)15)5-10(12)9(6)4-7/h1-5,12H,11H2,(H,13,14,15)
InChIKey HBZVNWNSRNTWPS-UHFFFAOYSA-N

6-Amino-4-hydroxy-2-naphthalenesulfonic acid - Physico-chemical Properties

Molecular FormulaC10H9NO4S
Molar Mass239.25
Density1.4338 (rough estimate)
Boling Point458℃[at 101 325 Pa]
Water Solubility4.5g/L(hot water)
Vapor Presure0Pa at 25℃
Appearancepowder to crystal
ColorWhite to Gray to Brown
pKa-0.20±0.40(Predicted)
Storage ConditionKeep in dark place,Sealed in dry,Room Temperature
Refractive Index1.6500 (estimate)
MDLMFCD00003973
Physical and Chemical Properties

The Pure product is white needle-like crystal or crystalline powder.

soluble in ethanol and ether, insoluble in water.
pure product is white needle-like crystal or crystalline powder. Soluble in ethanol and ether, insoluble in water.

previously, β-naphthylamine was used as a raw material for the production of γ-acid, while J-acid was produced as a by-product. However, due to the carcinogenic effect of beta-naphthylamine is no longer used. At present, G salt (2-naphthol -6,8-disulfonic acid double potassium salt) is used as the raw material, which is obtained by ammonification, alkali melting and acidification. Product Specification: HG2-205-80. The appearance was a light gray paste with a gamma acid content (by coupling value) greater than 55%. Raw material consumption quota: G salt (100%)1520kg/t, sulfuric acid (99%)1850kg/t, caustic soda (100%)1200kg/t, sulfur dioxide (industrial) 330kg/t, ammonia (99%)485kg/t.

UseIt is used as an intermediate for reactive dyes and direct dyes. For direct diazo black BH, Direct Dark Brown M, direct jujube GB, direct red F, direct Gray D, direct N and direct sun-resistant ash.

6-Amino-4-hydroxy-2-naphthalenesulfonic acid - Risk and Safety

Hazard SymbolsC - Corrosive
Corrosive
Risk Codes34 - Causes burns
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S27 - Take off immediately all contaminated clothing.
S28 - After contact with skin, wash immediately with plenty of soap-suds.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDsUN 2585 8/PG 3
WGK Germany1
RTECSQK1295250
ToxicityLD50 intraperitoneal in mouse: > 500mg/kg

6-Amino-4-hydroxy-2-naphthalenesulfonic acid - Upstream Downstream Industry

Downstream ProductsDirect Grey D

6-Amino-4-hydroxy-2-naphthalenesulfonic acid - Nature

Open Data Verified Data

pure product is white needle-like crystal or crystalline powder. Soluble in ethanol and ether, insoluble in water. Its alkaline solution has blue fluorescence and can be oxidized in air. The acidic solution was red-brown in case of ferric chloride and dark-red in case of bleaching powder.

Last Update：2025-06-10 22:55:16

6-Amino-4-hydroxy-2-naphthalenesulfonic acid - Preparation Method

Open Data Verified Data

2-naphthol -6,8-= sulfonic acid double potassium salt (G salt) was Alkali-melted with sodium hydroxide to obtain 2,8-hydroxy-6-naphthalene sulfonic acid sodium salt. After acidification, ammoniation, y acid ammonium salt, with sulfuric acid, that is to get the finished product.

Last Update：2022-01-01 10:56:27

6-Amino-4-hydroxy-2-naphthalenesulfonic acid - Introduction

Soluble in ethanol and ether, hardly soluble in water. In case of ferric chloride, it is dark red and purple. It reacts with nitrous acid to produce yellow insoluble diazo compounds. The coupling under acidic and alkaline conditions produces two azo compounds respectively.
Last Update：2022-10-16 17:29:40

6-Amino-4-hydroxy-2-naphthalenesulfonic acid - Application

Open Data Verified Data

intermediates for the manufacture of reactive dyes and direct dyes, such as for the manufacture of direct diazo black BH, Direct Dark Brown M, direct jujube red GB, direct red F, direct Gray D, direct Violet N, and direct suntan B, etc. It can also be used as an indicator.

Last Update：2025-08-19 16:24:40

6-Amino-4-hydroxy-2-naphthalenesulfonic acid - Safety

Open Data Verified Data

basically non-toxic. The iron drum is packed in plastic bags with a net weight of 50kg. Should be stored in a dry and ventilated warehouse, to prevent heating, to avoid sun exposure.

Last Update：2025-06-10 22:55:16

6-Amino-4-hydroxy-2-naphthalenesulfonic acid - Reference Information

LogP-1.39
EPA chemical substance information information provided by: ofmpeb.epa.gov (external link)
Use is mainly used as an intermediate of azo dyes, used in the manufacture of reactive and direct dyes
used as an intermediate for reactive and direct dyes. For direct diazo black BH, Direct Dark Brown M, direct jujube GB, direct red F, direct Gray D, direct N and direct sun-resistant ash.
production method previously, β-naphthylamine was used as a raw material for the production of γ-acid, and J-acid was also produced as a by-product. However, due to the carcinogenic effect of beta-naphthylamine is no longer used. At present, G salt (2-naphthol -6,8-disulfonic acid double potassium salt) is used as the raw material, which is obtained by ammonification, alkali melting and acidification. Product Specification: HG2-205-80. The appearance was a light gray paste with a gamma acid content (by coupling value) greater than 55%. Raw material consumption quota: G salt (100%)1520kg/t, sulfuric acid (99%)1850kg/t, caustic soda (100%)1200kg/t, sulfur dioxide (industrial) 330kg/t, ammonia (99%)485kg/t.
category toxic substances
toxicity grade poisoning
Acute toxicity intraperitoneal-mouse LD: >500 mg/kg
flammability hazard characteristics flammability; Toxic nitrogen oxide and sulfur oxide fumes from combustion
storage and transportation characteristics warehouse ventilation and low temperature drying
extinguishing agent dry powder, foam, sand, carbon dioxide, water mist
Last Update：2024-04-09 21:54:55
6-Amino-4-hydroxy-2-naphthalenesulfonic acid
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View History
6-Amino-4-hydroxy-2-naphthalenesulfonic acid
1,3-Dibromonaphthalene-2-ol
PPS-OH(液体)羟基丙烷磺酸吡啶嗡盐
Silane, trimethoxyoctyl-
Downstream Products for 6-Amino-4-hydroxy-2-naphthalenesulfonic acid
Direct Grey D
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